We are looking for postdocs currently. If interested please email scofield@musc.edu.

SCOFIELD LABORATORY

Addiction Neuroscience

  • Publications
    • Glutamate and Nitric Oxide Amperometry
    • Microglia and Ethanol Withdrawal
    • Cortical Dendritic Spines and Cocaine Addiction
    • Effects of Heroin on Astrocyte-Synapse Interaction
  • Current Lab Members
  • Lab Alumni
  • Science Cartoons
  • Lab Blog Posts
  • Contact
    • Glutamate and Nitric Oxide Amperometry
    • Microglia and Ethanol Withdrawal
    • Cortical Dendritic Spines and Cocaine Addiction
    • Effects of Heroin on Astrocyte-Synapse Interaction
  • Current Lab Members
  • Lab Alumni
  • Science Cartoons
  • Lab Blog Posts
  • Contact
       
     
       
     
Impacts of LPS and CIE on cortical microglia soma dimensions
       
     
True 3D Polygonal Convex Hull Rendering
       
     
Cortical microglia visualized with Iba1
       
     
       
     
       
     
Morphological analyses of individual cortical microglia after LPS or CIE treatment
       
     
Tile scan of cortical microglia with ryanodine receptor labeling
       
     
Project Visual Abstract
       
     
       
     
+
       
     
+
Rotating Iba1 Z-Series (Press Play)
Impacts of LPS and CIE on cortical microglia soma dimensions
       
     
+
Impacts of LPS and CIE on cortical microglia soma dimensions

See full article here in the Journal of Neuroscience Research

True 3D Polygonal Convex Hull Rendering
       
     
+
True 3D Polygonal Convex Hull Rendering
Cortical microglia visualized with Iba1
       
     
+
Cortical microglia visualized with Iba1
       
     
+
High Magnification Iba1 Staining In Motion
       
     
+
Microglia Modeling

This video depicts how individual microglia are imaged, digitally reconstructed and analyzed.

Morphological analyses of individual cortical microglia after LPS or CIE treatment
       
     
+
Morphological analyses of individual cortical microglia after LPS or CIE treatment

See full article here in the Journal of Neuroscience Research

Tile scan of cortical microglia with ryanodine receptor labeling
       
     
+
Tile scan of cortical microglia with ryanodine receptor labeling
Project Visual Abstract
       
     
+
Project Visual Abstract

This cartoon depicts the changes in microglial morphological characteristics we observed in the prelimbic cortex following immune activation or chronic intermittent ethanol exposure and withdrawal. This was the visual abstract for this study. Click here for the full publication at the Journal of Neuroscience Research

­
­